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nencki.gov.pl » Working Groups » Department of Neurophysiology »
Laboratory of Neuropsychology

Head
Elżbieta SZELĄG

Staff
Iwona ADAMASKA (doktorantka), Maria BRZYSKA, Monika LEWANDOWSKA (doktorantka), Justyna MĘDYGRAŁ (doktorantka), Aneta SZYMASZEK (doktorantka), Joanna SADOWSKA (technician), Katarzyna TRZEŚNIEWSKA, Andrzej SZCZEPANKIEWICZ (technician), Małgorzata WĘSIERSKA

Research profile

concern neurophysiology and neuropsychology of cognition in human and animal models in norm and pathology. Human studies are focused on temporal aspects of information processing, learning, language, memory and attention. Research involves normal subjects (children and adults, including Centenarians), patients showing different neurodegenerative diseases (stroke, focal brain damage, dementia, Alzheimer disease), cochlear implant users, as well as children who show various speech and/or language disorders, e.g. aphasia, deafness, stuttering, infantile autism. Animal studies are focused on neural substrates of learning, memory, auditory perception, cognitive coordination and cognitive flexibility.

Current research activities

the Laboratory is involved in neuropsychological basis of human and animal cognition. In human studies both behavioral and neuroimaging methods (fMRI) are devoted to temporal aspects of information processing, language, hemispheric asymmetry, normal chronological aging, neurodegeneration. Animal studies are focused on neural basis of memory in different strains of rats. A close cooperation with neurological clinics allows for studies on cognitive abilities in patients with brain damage, aphasia, hearing deficits as well as neurodevelopmental or neurodegenerative diseases. The studies are combined with behavioral, electrophysiological, fMRI, molecular, pharmacological, neuroanatomical and lesion techniques.

  • temporal aspects of information processing in norm and pathology;
  • speech therapy in different language disorders: aphasia, stuttering, infantile autism, hearing deficits;
  • neuropsychology of language restitution;
  • cognitive deficits in infantile autism;
  • neuropsychology of normal chronological aging, longevity and neurodegeneration;
  • neuropsychological assessment of early stages of Alzheimer disease;
  • neural basis of learning, spatial and recognition memory in rats;
  • comparative behavioral studies on memory in different strains of rats and different animal species;
  • neural basis of auditory recognition memory and auditory processing in rats.

Selected publications

Lewandowska M., Bekisz M., Szymaszek A., Szymaszek A., Wróbel A., Szeląg E. (2008) Towards electophysiological correlates of auditory perception of temporal order. Neurosci. Letters (in press)

Wesierska M., Klinowska H.D., Adamska I., Fresko I., Sadowska J., Albrecht J. (2006) Cognitive flexibility but not cognitive coordination is affected in rats with toxic liver failure. Behav. Brain Res. 171:70-77.

Szymaszek A., Szeląg, E., Śliwowska M. (2006)Auditory perception of temporal order in humans: the effect of age, gender, listener practice and stimulus presentation mode. Neurosci. Lett. 403:190-194.

Kowalska J., Szeląg E. (2006) The effect of congenital deafness on the duration judgement. J. Child Psychol. Psychiatry 47: 946-953.

Wesierska M., Dockery C., Fenton A.A. (2005) Beyond memory, navigation and inhibition: Behavioral evidence for hippocampus-dependent cognitive coordination in the rat. J. Neurosci. 25:2413-2419.



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Published at: 2008-04-25 11:09
 

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