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Department of Molecular and Cellular Neurobiology
Laboratory of Bioinformatics and Systems Biology
Laboratory of Calcium Binding Proteins
Laboratory of Epileptogenesis
Laboratory for Mechanisms of Transport Through Biomembranes
Laboratory of Molecular Basis of Brain Plasticity
Laboratory of Molecular Neurobiology
Laboratory of Neurobiology of Development and Evolution
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nencki.gov.pl » Working Groups » Department of Molecular and Cellular Neurobiology »
Laboratory of Epileptogenesis

Head
Katarzyna ŁUKASIUK

Staff
Marzena STEFANIUK (PhD student), Anna ŚLIWA (PhD student)

Research profile

Research is concentrated on molecular response to brain injury and molecular events leading to development of epilepsy. We particularly interested in alterations in gene expression leading to expression of spontaneous seizures in in vivo models of epileptogenesis and epilepsy as well as in development of new strategies influencing disease development. Laboratory is a member of the Network of European Neuroscience Institutes ENI-NET

Current research activities

  • search for new genes involved in development of epilepsy
  • investigation of compounds influencing immune system as a potential drugs for modification of epileptogenesis and epilepsy
  • role of neurogenesis in epileptogenesis and epilepsy

Selected publications

Lahtinen L, Lukasiuk K, Pitkanen A. (2006) Increased expression and activity of urokinase-type plasminogen activator during epileptogenesis. Eur J Neurosci. 24: 1935-1945

Lukasiuk K, Dabrowski M, Adach A, Pitkanen A. (2006) Epileptogenesis-related genes revisited. Prog Brain Res. 158: 223-41

Pirttila TJ, Lukasiuk K, Hakansson K, Grubb A, Abrahamson M, Pitkanen A. (2005) Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse. Neurobiol Dis. 20: 241-53

Lukasiuk K, Pitkanen A. (2004) Large-scale analysis of gene expression in epilepsy research: is synthesis already possible? Neurochem Res. 29: 1169-78



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Published at: 2007-03-09 18:00
 

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